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IF YOU DON'T HAVE A PRESCRIPTION?
Frontline Spot On is licensed for the treatment of Fleas and Ticks, and you can buy it here without prescription
Advantix 250 for Large Dogs 10kg-25kg. Prescription Required
Vetscriptions Price: £17.49
Typical Retail Price:
£28.75
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For the treatment and prevention of flea (Ctenocephalides canis, Ctenocephalides felis) infestations in dogs only.
Fleas on dogs are killed within one day following treatment. One treatment prevents further flea infestation for four weeks. The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
The product has a persistent acaricidal and repellent effect for four weeks (Rhipicephalus sanguineus, Ixodes ricinus) or three weeks (Dermacentor reticulatus), respectively, against tick infestations.
Ticks already on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore the removal of ticks already on the dog at the time of treatment is recommended, in order to prevent them from attaching and having a blood meal.
One treatment provides repellent (anti-feeding) activity against sand flies for two weeks (Phlebotomus papatasi) or three weeks (Phlebotomus perniciosus) respectively, against mosquitoes for two (Aedes aegypti) and four (Culex pipiens) weeks respectively and stable flies (Stomoxys calcitrans) for four weeks.
Advantix® Spot-on is an ectoparasiticide for topical use containing imidacloprid and permethrin . This combination acts as an insecticide, acaricide and as a repellent.
Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified as a chloronicotinyl nitroguanidine. Imidacloprid is effective against adult fleas and larval flea stages. In addition to the adulticide flea efficacy of imidacloprid, a larvicidal flea efficacy in the surroundings of the treated pet has been demonstrated. Larval stages in the dog`s immediate surroundings are killed following contact with a treated animal. It has a high affinity for the nicotinergic acetylcholine receptors in the post-synaptic region of the central nervous system (CNS) in insects. The ensuing inhibition of cholinergic transmission in insects results in paralysis and death of the parasite.
Permethrin belongs to the type I class of pyrethroid acaricides and insecticides and also acts as repellent. Pyrethroids affect the voltage-gated sodium channels in vertebrates and non-vertebrates. Pyrethroids are so called “open channel blockers” affecting the sodium channel by slowing both the activation and the inactivation properties thus leading to hyperexcitability and death of the parasite.
In the combination of both substances, it has been shown imidacloprid functions as the activator of arthropod ganglion and therefore increases the efficacy of permethrin.
The product provides repellent (anti-feeding) activity against ticks, sand flies and mosquitoes, thus preventing the repelled parasites from taking a blood meal and thus reducing the risk of disease transmission (e.g. Borreliosis, Rickettsiosis, Ehrlichiosis, Leishmaniasis). However, there may be an attachment of single ticks or bites by single sand flies or mosquitoes. For this reason, a transmission of infectious diseases by these parasites cannot be completely excluded if conditions are unfavourable. The product provides repellent (anti-feeding) activity against stable flies thereby assisting in the prevention of fly-bite dermatitis.
There is no known interaction with other medicaments or other forms of interaction.
IMPORTANT LEGAL INFORMATION: this is a Veterinary Prescription Only Medicine (POM-V), which can only be prescribed by a veterinary surgeon, but may be dispensed by another veterinary surgeon or pharmacist. You will need to post us the original signed prescription before we can send you the medicines.
See
Prescription Only Medicines for full instructions on how to obtain your pets
Prescription Only Medicines from Vetscriptions.
Click on
Advantix
for more product information from the UK National Office of Animal Health.
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