Prescription Anti-Epileptic Medication for Canine Seizure Control

Phenoleptil® Tablets are a Prescription Only Medicine – Veterinary (POM-V, Controlled Drug Schedule 3) containing phenobarbital, one of the most widely prescribed anti-epileptic medications in veterinary practice. They are used in the long-term management of epilepsy in dogs, helping to reduce the frequency and severity of seizures.

Epilepsy is one of the most common neurological conditions in dogs, and without treatment it can significantly affect quality of life. Phenoleptil helps stabilise brain activity, offering dogs and their owners greater control and reassurance.

Phenoleptil is available in four different strengths — 12.5mg, 25mg, 50mg, and 100mg — making it suitable for precise weight-based dosing across all breeds, from small companions to giant dogs.

Key Benefits:

• Effective long-term control of epilepsy in dogs

• Reduces seizure frequency and severity

• Available in multiple strengths for tailored dosing

• Scored tablets allow accurate dose adjustment

• Licensed specifically for veterinary use in dogs

• Controlled drug (CD Sch 3) for regulated, safe use

Active Ingredient:

• Phenobarbital – a barbiturate that reduces abnormal electrical activity in the brain, helping to prevent epileptic seizures.

Indications:

• Management of generalised epilepsy in dogs

• Long-term treatment of idiopathic or symptomatic epilepsy

• May be used alongside other anti-epileptic medicines if prescribed by a vet

Available Strengths:

• Phenoleptil 12.5mg Tablets – suitable for small dogs or for initiating treatment

• Phenoleptil 25mg Tablets – for small to medium-sized dogs

• Phenoleptil 50mg Tablets – widely used for medium to large breeds

• Phenoleptil 100mg Tablets – designed for large and giant breed dogs requiring higher doses

Directions for Use:

• Administer orally as directed by your veterinarian

• Dose depends on your dog’s bodyweight, seizure history, and blood test results

• Tablets can be given with or without food but should be given at the same times every day

• Regular blood monitoring is required to ensure effective and safe drug levels

• Never stop treatment suddenly without veterinary advice

Important Safety Information:

• Prescription Only Medicine – Veterinary (POM-V, Controlled Drug Sch 3)

• A valid veterinary prescription is required for supply

• Not for use in dogs with severe liver impairment

• Use with caution in dogs with existing health conditions

• Possible side effects include mild sedation, increased appetite, or thirst (these often reduce over time)

• Overdose can be serious — always store securely and follow dosing instructions carefully

Storage:

• Store in original packaging below 25°C

• Controlled drug: store securely, out of reach of children and animals

Legal Category: POM-V.

To find details on all veterinary medicinal products currently authorised in the UK, please see the VMD's Product Information Database.

IMPORTANT LEGAL INFORMATION: This is a veterinary-prescription-only medicine (POM-V) that can only be prescribed by a veterinary surgeon but may be dispensed by another veterinary surgeon or pharmacist.